Other Information: Do not use if printed sealed pouch is torn, open or incompletely sealed. Do not use if seal over tube opening has been punctured. Do not purchase if carton is open. Store at 20 - 25 degrees C (68 - 77 degrees F). This is a 1-dose treatment. Most women do not get complete relief of their symptoms in just 1 day. Most women get some improvement in 1 day and complete relief by 7 days.